Hydroamination/Heck reaction sequence for a highly regioselective one-pot synthesis of indoles using 2-chloroaniline.
نویسندگان
چکیده
A one-pot indole synthesis consisting of a highly regioselective TiCl(4)-catalyzed hydroamination and a 5-endo Heck cyclization starting from 2-chloroaniline is described, using an in-situ generated, sterically hindered imidazol-2-ylidene palladium complex.
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ورودعنوان ژورنال:
- Chemical communications
دوره 24 شماره
صفحات -
تاریخ انتشار 2004